A Type VI Secretion System Trans-Kingdom Effector Is Required for the Delivery of a Novel Antibacterial Toxin in Pseudomonas aeruginosa

Pseudomonas aeruginosa has evolved multiple strategies to disarm and take advantage of its host.For this purpose, this opportunist pathogen has particularly developed protein secretion in the surrounding medium or injection into host cells.Among this, the type VI secretion system (T6SS) is utilized to deliver effectors into eukaryotic host as well

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Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interference.

Cathepsin-like enzymes have been identified as potential targets for drug or vaccine development in many parasites, as their functions appear to be essential in a variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion.Functional analysis of Caenorhabditis elegans cat

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